A mean first passage time genome rearrangement distance
Francis, A. R. & Wynn, H. P.
(2020).
A mean first passage time genome rearrangement distance.
Journal of Mathematical Biology,
80(6), 1971-1992.
https://doi.org/10.1007/s00285-020-01487-w
(2020).
A mean first passage time genome rearrangement distance.
Journal of Mathematical Biology,
80(6), 1971-1992.
https://doi.org/10.1007/s00285-020-01487-w
This paper introduces a new way to define a genome rearrangement distance, using the concept of mean first passage time from probability theory. Crucially, this distance provides a genuine metric on genome space. We develop the theory and introduce a link to a graph-based zeta function. The approach is very general and can be applied to a wide variety of group-theoretic models of genome evolution.