Reporting of clinical trial uncertainties with new cancer drugs in journal publications and clinical guidelines

Cherla, A., Wagner, A. K., Wouters, O. J.ORCID logo, Woloshin, S., Davis, C., Mossialos, E.ORCID logo & Naci, H.ORCID logo (2025). Reporting of clinical trial uncertainties with new cancer drugs in journal publications and clinical guidelines. JAMA, 334(16), 1480 - 1482. https://doi.org/10.1001/jama.2025.13917
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This study assesses the reporting by journal publications and National Comprehensive Cancer Network (NCCN) guidelines of clinical uncertainties identified by the US Food and Drug Administration’s (FDA) Benefit-Risk Framework pertaining to cancer drugs approved in 2019-2022.

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