Comparing prospective incident severe acute respiratory syndrome Coronavirus 2 infection rates during successive waves of Delta and Omicron in Johannesburg, South Africa
Sokhela, Simiso; Bosch, Bronwyn; Hill, Andrew; Simmons, Bryony
; Woods, Joana; Johnstone, Hilary; Madhi, Shabir; Qavi, Ambar; Ellis, Leah; Akpomiemie, Godspower; +9 more...Bhaskar, Esther; Levi, Jacob; Falconer, Jonathan; Mirchandani, Manya; Perez Casas, Carmen; Moller, Karlien; Pilkington, Victoria; Pepperrell, Toby; and Venter, Willem Daniel Francois
(2022)
Comparing prospective incident severe acute respiratory syndrome Coronavirus 2 infection rates during successive waves of Delta and Omicron in Johannesburg, South Africa.
Open Forum Infectious Diseases, 9 (12): ofac587.
ISSN 2328-8957
; Woods, Joana; Johnstone, Hilary; Madhi, Shabir; Qavi, Ambar; Ellis, Leah; Akpomiemie, Godspower; +9 more...Bhaskar, Esther; Levi, Jacob; Falconer, Jonathan; Mirchandani, Manya; Perez Casas, Carmen; Moller, Karlien; Pilkington, Victoria; Pepperrell, Toby; and Venter, Willem Daniel Francois
(2022)
Comparing prospective incident severe acute respiratory syndrome Coronavirus 2 infection rates during successive waves of Delta and Omicron in Johannesburg, South Africa.
Open Forum Infectious Diseases, 9 (12): ofac587.
ISSN 2328-8957
In high-risk individuals in Johannesburg, during the Delta coronavirus disease 2019 wave, 22% (125/561) were positive, with 33% symptomatic (2 hospitalizations; 1 death). During Omicron, 56% (232/411) were infected, with 24% symptomatic (no hospitalizations or deaths). The remarkable speed of infection of Omicron over Delta poses challenges to conventional severe acute respiratory syndrome coronavirus 2 control measures.
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