Psychological and demographic characteristics of 368 patients with dissociative seizures: data from the CODES cohort

Goldstein, L. H., Robinson, E. J., Mellers, J. D., Stone, J., Carson, A., Chalder, T., Reuber, M., Eastwood, C., Landau, S., McCrone, P., +7 more...Moore, M., Mosweu, I., Murray, J., Perdue, I., Pilecka, I., Richardson, M. P. & Medford, N. (2020). Psychological and demographic characteristics of 368 patients with dissociative seizures: data from the CODES cohort. Psychological Medicine, https://doi.org/10.1017/S0033291720001051
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Background We examined demographic, clinical, and psychological characteristics of a large cohort (n = 368) of adults with dissociative seizures (DS) recruited to the CODES randomised controlled trial (RCT) and explored differences associated with age at onset of DS, gender, and DS semiology.MethodsPrior to randomisation within the CODES RCT, we collected demographic and clinical data on 368 participants. We assessed psychiatric comorbidity using the Mini-International Neuropsychiatric Interview (M.I.N.I.) and a screening measure of personality disorder and measured anxiety, depression, psychological distress, somatic symptom burden, emotional expression, functional impact of DS, avoidance behaviour, and quality of life. We undertook comparisons based on reported age at DS onset.

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